School of Medicine

Wayne State University School of Medicine

Clinical Services

Clinical Diagnostic Expertise

The staff at the Wayne State University Multiple Sclerosis Center are nationally recognized for their expertise in multiple sclerosis and related central nervous system disorders including:

  • Transverse Myelitis
  • Neuromyelitis Optica (NMO) or Devic’s disease
  • Pediatric multiple sclerosis
  • ADEM or acute disseminated encephalomyelitis

Furthermore, a large number of consultations are provided for patients seeking a second opinion for:

  • High risk pregnancy multiple sclerosis management
  • Rapidly progressive multiple sclerosis
  • Abnormal brain MRI scans

Several conditions can mimic symptoms of multiple sclerosis. To make the diagnosis of MS, a good quality, high-resolution brain MRI scan is critical as well as a thorough diagnostic approach. Some of the conditions that can mimic MS include:

  • CNS Lupus
  • CNS Sarcoidosis
  • Lyme’s disease
  • CNS Vasculitis
  • CNS viral infections
  • Childhood and adult leukodystrophies

Diagnostic Services
MRI Scans:

Six MRI scanners with state of the art software and image capabilities are available at the DMC/WSU MS Center. Brain and spinal cord MRI scans including high-field MRI scanners provide unique images not available with routine MRI scanners. These special sequences can provide highly sensitive information regarding tissue injury in the brain. Sedation can be provided for patients who are claustrophobic.

Laboratory testing for MS:

Special blood tests that help distinguishing MS and from other diseases that may mimic MS. This could include diseases such as Lupus, Sarcoidosis, Lyme disease, or other conditions.

Lumbar Puncture (also known as spinal tap):

This procedure can be done as an outpatient in the Neurology Clinic by the neurologist or under X-ray guidance by the radiologist.

Evoked potential tests including:

  • Visual Evoked Potentials (VEP)
  • Somatosensory Evoked Potentials (SSEP)
  • Brainstem Auditory Evoked Potentials (BAEP)

Treatment Services
 

Six FDA-approved treatments:

  • Avonex, Betaseron, Copaxone, Rebif, Novantrone, and Tysabri

Other Off-label treatments for multiple sclerosis:

  • Cyclophosphamide (cytoxan), cellcept, azathioprine, methotrexate, rituximab, campath, and IVIG

Special symptomatic treatments:

  • 4-Aminopyridine (4-AP)
  • Low dose naltrexone (LDN)

Plasmapheresis or Plasma exchange (PLEX) for severe relapses

Intrathecal baclofen for severe spasticity

Experimental Clinical Trials (see Clinical Trials section)

Consultative Services

  • Physical Medicine & Rehabilitation
  • Neuropsychology
  • Urology
  • Social Work Case Manager
  • Visiting Nurse Association
  • Counselor
  • Psychiatry